Cystic fibrosis can be treated by _______________ in gene therapy. A) TGF-B B) TPA C) DNase D) BGH
Cystic fibrosis can be treated by _______________ in gene therapy. A) TGF-B B) TPA C) DNase D) BGH

Correct option:(C)DNase

Solution:

  • Cystic Fibrosis is an autosomal recessive genetic disease that affects the lungs.
  • Characterized by the thick and sticky mucus due to defective gene.
  • Occurs due to mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
  • Treated by gene therapy using DNase.
  • DNase is a DNA-destroying enzyme that breaks DNA strands remained by dying cells.
  • DNase I reduces sputum viscosity in the lungs of CF patients as viscous sputum causes recurrent infections and affects lung function.