Describe the process of development of an ovum from an oogonium in human female.
Describe the process of development of an ovum from an oogonium in human female.

Describe the process of development of an ovum from an oogonium in human female.

Answer: The formation of an ovum from oogonium is known as oogenesis. Multiplication, growth, and maturation are the three stages.

Oogenesis begins in the female foetus’ embryonic ovaries.

The cell begins to divide (oogonia) and enters prophase 1 of the meiotic cycle, when it is momentarily arrested and referred to as a primary oocyte.

A layer of granulosa cells surrounds each primary oocyte, forming a primary follicle. Many of them degenerate, leaving only 60000 to 80000 primary follicles by puberty.

It is then encircled by more granulosa layers and a new theca, forming a secondary follicle.

These develop into the tertiary follicle, which is distinguished by the presence of a fluid-filled cavity known as the Antrum. The primary oocyte matures and completes its first meiotic division at this stage.

The asymmetrical division results in the development of a big secondary oocyte and a small polar body. The secondary oocyte produces a new layer called Zona pellucida around itself when the tertiary follicle matures into a Graafian follicle. This follicle ruptures during ovulation to release a secondary oocyte/ovum (which completes 2nd meiotic division just prior to fertilization)

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