3. Discuss the significance of heavy isotope of nitrogen in the Meselson and Stahl’s experiment.
3. Discuss the significance of heavy isotope of nitrogen in the Meselson and Stahl’s experiment.

Solution:

In Meselson and Stahl’s experiment, a heavy isotope of nitrogen revealed that the DNA is of intermediate density between N14 and N15. This revealed that the hybrid DNA has one N14 strand and one N15 strand, indicating that the DNA is semi-conservative.