Explain the autoregulatory mechanism of GFR.
Explain the autoregulatory mechanism of GFR.

Solution: The auto regulating mechanism in the kidneys regulates the glomerular filtration rate. It is mediated by the juxtaglomerular apparatus, a microscopic structure located between the returning distal convoluted tubule and the vascular pole of the same nephron’s renal corpuscle. It controls the glomerular filtration rate and the passage of blood through the kidneys. The juxtaglomerular cells are stimulated for the release of renin when the glomerular filtration rate decreases. The glomerular blood flow is triggered, and the GFR returns to normal. Renin activates the renin-angiotensin system, which causes GFR to return to normal.