Answer: The replication process begins in specific locations known as replication origins. Replication takes place inside a small opening in the DNA known as a Y-shaped replication fork (uncoiling of DNA is by some enzymes eg Helicase and topoisome rase), DNA dependent DNA polymerase catalyses nucleotide polymerization in the 5′ – 3′ directions. Deoxyribonucleotides serve as substrates and provide energy for the process. New strands created on the 3′-5′ template are continuous, while those formed on the 5-‘3’ template are discontinuous. The discontinuously formed fragments are united by the enzyme DNA ligase.
Explain the mechanism of DNA replication. Highlight the role of enzymes in this process.
Explain the mechanism of DNA replication. Highlight the role of enzymes in this process.