Broad-spectrum antibiotics are medicines that work against a wide range of gram-negative and gram-positive bacteria. Chloramphenicol, for example.

Acute fever, typhoid, meningitis, dysentery, TB, and certain forms of urinary tract infection are all treated with this drug. Vancomycin and ofloxacin are the other two broad-spectrum antibiotics. Amoxicillin and ampicillin, both synthesized from penicillin, are broad-spectrum antibiotics.